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438 clinical trials found.
Surgery and Rehabilitation

We are doing this study to determine the effect of single vs multiple arterial revascularization (this is the restoration of blood flow to an organ) for female patients undergoing coronary artery bypass surgery (CABG).

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an investigational drug called OBI-3424 is a safe and effective option for patients with leukemia or lymphoma.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if either of 2 different, experimental drug regimens (ramucirumab plus paclitaxel or FOLFIRI) is an option for treating small bowel cancer that has not responded to therapy.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare the early treatment (before you have cancer symptoms) of Venetoclax and Obitnutuzumab (V-O) to the usual treatment of V-O after you have cancer symptoms. This study will help doctors figure out if early treatment is better, the same, or worse than the usual approach of waiting until the patient has cancer symptoms before starting treatment.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to compare the usual treatment for neuroendocrine carcinomas to using atezolizumab plus the usual treatment. Another purpose is to compare using atezolizumab just at the beginning of treatment to continuing it beyond the initial treatment.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if either of two experimental drugs (mosunetuzumab and polatuzumab vedotin) is a safe and effective option for people who have had CAR T-cell therapy. We want to know how each drug works on its own as well as in combination with each other when given after CAR T-cell therapy is complete.

Compensation: No
Oncology
Surgery and Rehabilitation

We are doing this study to collect data and samples to store them for future research. We hope the data and samples will lead to improved treatment of patients who are seriously ill or have been injured.

Compensation: No
Ages: 18-90
Non-Oncology
Duke University Hospital
Immune System and Infections

This is a biosample collection study for people in the Surgical Critical Initiative Tissue and Data Acquisition Study If you join this study, you will: - Have blood drawn (an extra 2 teaspoons) at time of your injury or surgery, on Days 1, 3 and 7 after your injury or surgery, and weekly while you are in the hospital. We may also collect fluid or tissue from your wound and pictures of it We will also collect blood near time of surgery or if you get worse. We will also ask to use data collected under TDAP for analyses.

Compensation: No
Non-Oncology