Clinical Trials Directory

402 clinical trials found.
Lungs and Breathing

We are doing this to develop a test that could help predict a common complication after lung transplant called primary graft dysfunction (PGD). Examining the medical records of transplant recipients and their donors will help us find the data we need to create this prediction tool.

Compensation: No
Non-Oncology
Brain and Spine Metastasis

We are doing this study to find out if an investigational drug called PRL-02 (the study drug) is a safe and effective method to lower levels of male hormones during treatment for prostate cancer. The study drug is an injectable form of a drug called abiraterone.

Compensation: No
Oncology
Research for Healthy Adults

We created this registry to have a database of healthy people who are interested in participating in research about lung health and breathing. We will use this registry to reach out to people and notify them about research studies in which they might be interested.

Compensation: No
Ages: 18-110
Non-Oncology
Remote/online
Lungs and Breathing

We maintain this registry to have a database of people with any type of lung or breathing disorder who are interested in participating in research about their lung condition.

Compensation: No
Ages: 18-65
Non-Oncology
Duke University Hospital
Primary Brain and Spinal Cord Tumors

We are doing this study to find out how safe and effective an experimental drug called MVR-C5252 (the study drug) is for people with advanced brain cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Research for Children and Teenagers

If you choose to join this study, we will ask you questions about:

  • Your life at home
  • Your life at school
  • Your medical needs
We will ask you to answer these questions each year during one of your regular clinic visits.

Compensation: No
Non-Oncology
Bones, Joints and Muscles

We are doing this study to get a better understanding of how exercise affects the motion and mechanics of the shoulder joint in people who have shoulder instability and are planning to have shoulder surgery. We hope the information we gain from this study can improve treatment methods for injuries like shoulder dislocations or rotator cuff tears.

Compensation: Yes
Ages: 15-35
Non-Oncology
Duke University Hospital, Other
Primary Brain and Spinal Cord Tumors

We are doing this study to find out how safe and effective it is to give people with recurrent glioblastoma two infusions of an experimental drug called lerapolturev (the study drug) in residual disease (within tumor margins) after surgery. After these two doses, we will give further doses of the study drug as injections in the subcutaneous area (under the skin) around the lymph nodes of the head and neck. We also want to know how well the study drug works compared to lomustine, which is a standard form of chemotherapy (drug used to kill cancer cells).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital