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We are doing this study to learn more about how 2 different classes of diabetes medications help lower the risk of heart disease. The types of diabetes medications that have been shown to reduce the risk of new or worsening heart disease are SGLT2 inhibitors and GLP-1 receptor agonists. We don't know which of these drugs might be preferable to reduce heart disease risk for diabetes patients, and we hope this study can help us find out which drug(s) may be the most appropriate for most patients.

We are doing this study to find out if we can identify biomarkers that indicate the presence of ovarian cancer or indicate that it is likely to develop. Biomarkers are substances that can be released from cancer cells into the blood and can provide information on the following things: changes to someone's genes or DNA, how cancer cells will respond to cancer treatment, and whether cells are becoming resistant (no longer responding) to cancer treatment.

We are doing this study to find out whether it is possible to use genetic information from your tumor sample in order to test if your tumor will be sensitive to oxaliplatin (the standard of care treatment for your disease).

We are doing this study to get a better understanding of what predicts severe pain in teenagers and young adults living with sickle cell disease.

We are doing this study is to compare the two most common corrective surgeries in the U.S. for uterovaginal prolapse (UVP). For now, no high-quality data exists to help guide patients and surgeons on the best option for treatment of UVP. The goal of the study is to find out which surgery works best from a patient's perspective and has the lowest number of short-term and long-term medical problems.

We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease. *The study drug is a statin, which is usually used to help lower cholesterol levels.

We are doing the Project HOPE study to better understand the health outcomes of moms and babies. We want to identify factors that contribute to poor birth outcomes, which might include premature both or low birthweight. We also want to learn more about what contributes to positive or negative maternal health outcomes, and longer-term child health and well-being outcomes, including academic achievement and physical development.

We are doing this study to find better methods to help cancer patients and cancer survivors stop smoking. In addition to improving overall health, we also want to see if quitting smoking can reduce pain.