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If you decide to be part of the study, here's what will happen: - You'll get check-ups and blood tests. - Doctors will take pictures of your brain using special machines called CT or MRI. - Your heart will be checked with a test called an ECG. - You'll have a special treatment called Exablate to help medicine reach your brain better. You might get up to 6 rounds of treatment over about 15 weeks, but only if the doctors thinks it's safe to keep going.

We are doing this study to learn more about why the right side of the heart doesn't work well in certain heart conditions. We're using heart tissue samples from people with specific heart problems to help us make these important discoveries.

We are doing this study to collect blood and cerebrospinal fluid samples from patients who have breast cancer that has spread to the brain and/or spinal cord. We hope that by analyzing these samples, we can find out how effective different cancer medications are at treating metastases to the leptomeninges (tissue that surrounds the brain and spinal cord). We also want to do genetic testing on these samples to look for cancer mutations that can give us clues about how people might respond to different therapies or which therapies are most likely to be helpful.

We are doing this study to find out if an experimental technology is a safe and effective way to administer treatment for relapsed and/or refractory multiple myeloma (RRMM). We want to know if giving the drug isatuximab as an injection under the skin works as well as giving this same drug as an intravenous (IV) infusion. The drug combination of isatuximab, carfilzomib, and dexamethasone is approved for the treatment of RRMM, but the current standard of care is to give isatuximab through an IV.

If you take part in this study, you will visit the clinic at least ten times over about twenty seven months. Most visits will last two days, but some may take three days if needed. You will be placed into one of two groups by chance. One group will receive the study medicine, and the other group will receive a sham injection, which looks like a real injection but has no medicine.

We will collect health information from medical records and biologic samples at standard of care visits related to your lung transplant. Samples collected may include blood, tissue, and fluids.

We are doing this study to find out if an experimental drug called LY3962673 (the study drug) is a safe and effective option for cancer that has a KRAS G12D mutation. We are also trying to find the best dose level to use.