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In this study, people will be placed into one of two groups by chance. One group will receive a one time treatment of iron given through a vein. The other group will receive a placebo, which is a salt water infusion with no medicine. Participants will not know which treatment they receive. The first visit will be in person and may take a few hours. After that, most follow up visits will be done from home by phone or video. The study lasts about six months, and there will be a final in person visit at the end.
We are doing this study to compare 2 different approaches for patients who have surgery to remove non-small cell lung cancer (NSCLC). We want to see if giving patients an immunotherapy drug called durvalumab (the study drug) after surgery has different outcomes than the usual approach, which is to closely monitor a patient's condition for any changes.
We are doing this study to find out if images taken of the eye using a special type of camera placed inside a surgical microscope, called Microscope Integrated Optical Coherence Tomography (MIOCT), will give us new information during surgery that will improve both how we perform eye surgery and the results of surgery.
We are doing this study to find the most effective, safe dose of an experimental drug called INT230-6 (the study drug) in people with recurrent, inoperable, or metastatic soft tissue sarcomas (STS). We also want to know how well it works compared to the usual treatments for people with this diagnosis.