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If a child joins this study, they will be placed into one of two groups by chance. One group will receive a medicine called Cipepofol, and the other group will receive a medicine called Propofol. These medicines are given through a vein to help the child fall asleep before surgery. Most children will receive Cipepofol, while a smaller number will receive Propofol. All children will still receive normal anesthesia care during surgery. Before surgery, there will be a screening visit with tests such as a physical exam, blood tests, urine tests, heart checks, and vital signs. On the day of surgery, more checks will be done. After surgery, the study team will call three times to see how the child is doing. Participation lasts for up to 29 days after surgery.

We are doing this study to understand how hand transplantation can help you with your daily activities compared to before the transplant.

We are doing this study to better understand how HIV affects the body.

The purpose of this study is to find out if combining a bispecific antibody with a drug called selinexor (XPOVIO) is a safe and effective option for multiple myeloma patients whose disease has returned after treatment or did not adequately respond to treatment.

We are doing this study to collect blood samples that may be used for the following:

• To make sure equipment and assays are working properly
• Staff training
• Researching assay development (an assay is a laboratory test)

Participants will attend 4 study visits over about 16 weeks. They will be randomly assigned to try two different study hearing aids, wearing each one for 4 weeks. At each visit, participants will complete hearing tests and questionnaires about their experience before returning the hearing aids at the end of the study.