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We are doing this study to find the safest and most effective dose of an experimental drug called ZL-1310 (the study drug). We want to know if this drug can be beneficial for people with small cell lung cancer (SCLC) that progressed after at least one round of chemotherapy.

This study lasts about 16 weeks. If you join, you will go to four visits in person and have one visit on Zoom. You will fill out weekly online surveys and answer questionnaires. The study team will also collect some information from your medical record. You will have fasting blood tests before you start taking zinc and again while you are taking zinc. You will also give urine samples at several visits. There are two groups in the study, and you will be placed into one by chance. One group takes 25 milligrams of zinc and the other group takes 40 milligrams of zinc. You should stay on your regular medicines during the study and avoid starting new long term treatments. You cannot take any extra zinc outside of the study.

We are doing this study to find out if a drug called zolbetuximab, when it is combined with pembrolizumab and standard chemotherapy, is a safe and effective option for treating stomach cancer.