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We are doing this study to find out if giving patients a drug called atezolizumab before and after surgery for recurrent glioblastoma can improve how their cancer responds.

The purpose of this study is to better understand how prenatal maternal health, such as higher body mass, and well-being, such as mental health, are related to early child development. We are especially interested in identifying the factors that influence young children's ability to regulate their emotions. We hope that any new information we learn from this study could benefit young children in the years to come. El propósito de este estudio es comprender mejor cómo la salud prenatal de la madre, como una mayor masa corporal, y el bienestar, como la salud mental, están relacionados con el desarrollo tempano de los niños. Estamos especialmente interesados en identificar los factores que influyen en la capacidad de los niños pequeños para regular sus emociones. Esperamos que cualquier información nueva que obtengamos de este estudio pueda beneficiar a los niños pequeños en los años venideros.

We are doing this study to see how tucatinib, trastuzumab, and mFOLFOX6 work to treat cancer of your colon or rectum that is HER2-positive with mFOLFOX6 alone or combined with bevacizumab.

The study uses a placebo, which is a pill that looks real but has no medicine in it. This helps researchers see how well the study drug works. People who join the study can keep taking some of their regular medicines as long as these medicines follow the study rules.

This study follows about 40 mothers and their children who have a condition called tuberous sclerosis complex. The children are 10 years old or younger. The study looks at information from pregnancies, including whether the mother took certain medicines during pregnancy or not. To take part, participants will give consent online, have a short phone call, and complete surveys. With permission, the study team will collect medical records about the pregnancy and the child’s health from birth to now. There are no in person visits, treatments, or procedures. The study only collects information to help doctors learn more about how this condition and certain medicines may affect pregnancy and children.

This study is being done to find out if atropine eyedrops (0.05% atropine, 99.95% inactive solution) and/or special eyeglass lenses are an effective strategy to slow down the progression of myopia for young children with nearsightedness.

We are doing this study to compare the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib. We want to find out if adding gilteritinib to the usual treatment is beneficial for people with acute myeloid leukemia (AML).