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445 clinical trials found.

We are doing this study to find out if an experimental test for the detection of hepatocellular carcinoma (liver cancer) called Oncoguard® is a reliable and accurate means to detect the disease in its earliest stages.

Compensation: Yes
Ages: 55-110
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to learn if a new study drug called AMG-509 is safe and effective in men who have metastatic, castrate-resistant prostate cancer. AMG-509 is a type of drug that helps a type of immune cells called T cells find and kill prostate cancer cells. The first part of this study will test different doses of AMG-509 in men to learn what side effects the study drug causes and which doses are safe. The second part of the study will see if a safe dose of AMG-509 slows cancer growth. This study will also teach us how long AMG-509 stays in your body, and whether treatment with AMG-509 changes the genes and proteins found in your tumor cells.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Genitourinary Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called xaluritamig (the study drug). We want to know how well this drug works compared to the standard drugs for people who have metastatic castration-resistant prostate cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Brain and Spine Metastasis

We are doing this study to compare how safe and effective different drug combinations are for treating metastatic cancer.

Compensation: No
Oncology
Digestive System

We are doing this study to learn more about how androgens, a type of sex hormone, might affect women who have nonalcoholic fatty liver disease (NAFLD). We want to see if they play a role in how the disease effects women over time, and we also want to see what role these hormones might play in the relationship between NAFLD and polycystic ovary syndrome.

Compensation: Yes
Ages: 18-42
Non-Oncology
Duke University Hospital
Ear, Nose and Throat

We are doing this study to find out if it is necessary to treat people with antibiotics after nasal surgery. We want to know if antibiotics are helpful or not during the healing process after surgery.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called APL-5125 (the study drug) is a safe and effective for people with select types of gastrointestinal cancer. We are also trying to find the best dose of APL-5125 to use.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital