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402 clinical trials found.

We are doing this study to compare 2 different regimens for treating pancreatic cancer after surgery. We what find out how well patients do after they get a combination of the drugs cevumeran, atezolizumab, and mFOLFIRINOX compared to just getting mFOLFIRINOX alone. Cevumeran is an experimental drug that is made from your own cells that are obtained from blood and tissue samples. It is designed to activate your immune system against cancer cells in your body.

Compensation: No
Ages: 18-110
Duke University Hospital
Pregnancy Concerns

We are doing this study promote the importance of quitting smoking for pregnant women and to improve how providers can help their patients quit smoking.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital, Other
Research for Children and Teenagers

We are doing this study to find out if pictures taken of the back of the eye (retina) using a special type of camera called Optical Coherence Tomography (OCT) can predict how well a baby will be able to see and how their brain works at school age. El propósito de este estudio es determinar si las fotos tomadas del fondo de ojo (retina) usando una cámara especial que se llama Tomografía de coherencia Óptica (OCT), puede predecir la visión y como el cerebro funciona a la edad escolar.

Compensation: Yes
Ages: 0-50
Non-Oncology
Duke University Hospital
Skin Cancer - Melanoma

We are doing this study to find out if an experimental drug called MK-4280A (the study drug) is a safe and effective option for people who are diagnosed with different types of solid tumors. We are enrolling Arm A of this study, which is open to people diagnosed with cutaneous squamous cell carcinoma (cSCC).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an investigational drug called TP-3654 (the study drug) is a safe and effective treatment for myelofibrosis. The study drug will be tested at different doses to find out what effects, if any, it has on myelofibrosis.

Compensation: No
Oncology
Breast Cancer

We are doing this study to find out if an experimental drug called BGB-43395 (the study drug) is a safe and effective option for people with for breast cancer and other advanced solid tumors. We want to know how the study drug works on its own and in combination with other cancer drugs.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most safe and effective long-term dose of an experimental drug called zanubrutinib (the study drug) when it is given alone or in combination with other cancer drugs. We want to know how well this study drug works in people with B-cell cancers who are currently participating or previously participated in a BeiGene-sponsored study.

Compensation: No
Oncology
Eyes and Vision

We are doing this study to monitor the health of the cornea in participants with neovascular age-related macular degeneration (nAMD), also know as wet AMD, who receive an eye implant that continuously delivers the drug ranibizumab into the back of the eye.

Compensation: Yes
Ages: 55-89
Non-Oncology
Duke University Hospital