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445 clinical trials found.
Heart and Circulation

We are doing this study to learn more about the safety and effectiveness of the Medtronic Intrepid Transcatheter Mitral Valve Replacement System.   

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to see if the study drugs, domvanalimab and zimberelimab, are safe and effective for treating advanced or metastatic gastroesophageal adenocarcinoma.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to determine the safety and effectiveness of an experimental medical device called the GORE Ascending Stent Graft (ASG Device) for the treatment of aortic diseases.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Skin Cancer - Melanoma

We are doing this study to learn more about the effects of an experimental drug called RP1 (the study drug) for organ transplant recipients who have an advanced form of skin cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Eyes and Vision

We are doing this study to find out if an experimental drug called ixoberogene soroparvovec (the study drug) is a safe and effective option for people with neovascular age-related macular degeneration (wet AMD). We want to see how well it works compared to the currently approved standard treatment, Eylea® (aflibercept).

Compensation: Yes
Ages: 50-110
Non-Oncology
Duke University Hospital
Breast Cancer

We are doing this study to find out if a study drug called sacituzumab govitecan can improve outcomes for patients with high risk, early triple negative breast cancer (TNBC). We want to know if giving this drug in combination with pembrolizumab will work better than pembrolizumab on its own or better than pembrolizumab + capecitabine.

Compensation: No
Oncology
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called ASP2138 (the study drug) is a safe and effective option for people who have pancreatic cancer that can be treated with surgery. We want to know if the study drug has a benefit when it is taken by patients before their surgery who then have standard chemotherapy after their surgery.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital