Clinical Trials Directory

We are doing this study to find the most effective, safe dose of an experimental drug called petosemtamab (the study drug). We also want to know how well it works compared to the standard treatments used for metastatic/recurrent head and neck squamous cell carcinoma (HNSCC).

We are doing this study to identify new signs and symptoms of inflammatory bowel disease (IBD) in children and young adults. We want to improve at predicting the future course of IBD so that we can treat it better and faster. We also hope this study will help us learn how IBD develops so that we can make new treatments for IBD.

We are doing this study to find out if nighttime dosing of a sedative called dexmedetomidine (the study drug) can reduce the occurrence of delirium (a state of mental confusion) in older adults who have heart surgery.

We are doing this study to learn more about how well a study intervention works to reduce distress caused by misophonia. This intervention combines neurostimulation and skills-based training that is designed to help people think differently.

We are doing this study to find the most effective, safe dose of an experimental drug called bomedemstat or hydroxyurea in people with essential thrombocythemia (ET). We also want to know which of these options works best for most people.

We are doing this study to find out if adding a drug called enasidenib (the study drug) to the standard treatment for myelodysplastic syndrome (MDS) can improve the likelihood of achieving complete remission. The study drug is approved for acute myeloid leukemia (AML), but is not approved for the treatment of MDS.

We are doing this study to find out if giving patients a drug called atezolizumab before and after surgery for recurrent glioblastoma can improve how their cancer responds.

This study does not give any medicine or treatment. Instead, it includes a few short visits over about four weeks. People who join will go to the clinic up to three times. During the first visit, they will sign forms, talk about their health history, get a physical exam, have their blood pressure checked, and give blood and urine samples without needing to fast. For the second visit, they will take a small pill called dexamethasone at home the night before. Then they will come back to the clinic for a blood test while fasting. This test checks hormone levels. Some people may need a third visit. If their hormone levels are high, they will give more blood and schedule a special scan of their adrenal glands. This study is not a treatment study. It is meant to help doctors learn more about hormone levels in people with hard-to-control high blood pressure.