Clinical Trials Directory

433 clinical trials found.
Eyes and Vision

This study is being done to find out if atropine eyedrops (0.05% atropine, 99.95% inactive solution) and/or special eyeglass lenses are an effective strategy to slow down the progression of myopia for young children with nearsightedness.

Compensation: Yes
Ages: 5-11
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to learn more about the differences in the muscle and blood of people that have Peripheral Arterial Disease (PAD).

Compensation: No
Non-Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib. We want to find out if adding gilteritinib to the usual treatment is beneficial for people with acute myeloid leukemia (AML).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if 2 different experimental drug combinations can improve outcomes for people who are newly diagnosed with AML. We want to compare the outcomes from the standard treatment (cytarabine + daunorubicin) to the following experimental regimens:

  • Venetoclax + cytarabine + daunorubicin
  • Venetoclax + azacitidine

Compensation: No
Ages: 18-59
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare different experimental drug regimens to the usual treatment (cytarabine and daunorubicin) for acute myeloid leukemia (AML). We want to find out which options have the best outcomes. The different drug combinations we will be testing against the usual treatment are:

  • daunorubicin and cytarabine liposome
  • cytarabine and daunorubicin with venetoclax
  • azacitidine and venetoclax
  • daunorubicin and cytarabine liposome with venetoclax

Compensation: No
Ages: 18-59
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to see if blood and bone marrow samples can be tested in a timely manner that allows for the detection of certain markers that could guide cancer treatment.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
COVID-19

We are doing this study to learn more about changes in nasal tissue in people that have COVID-19. Many COVID-19 patients have reported a change in sense of smell and we would like to find out why that is.

Compensation: No
Non-Oncology