Clinical Trials Directory

433 clinical trials found.
Research for Children and Teenagers

We are using you or your child's medical information in this study to better understand the diagnosis, treatment, and complications of Spina Bifida.

Compensation: No
Ages: 0-110
Non-Oncology
Remote/online, Duke University Hospital
Brain, Spinal Cord and Nerves

We created the Registry for Brain Health to help you improve your brain health and get involved in research studies. The number of people in North Carolina affected by memory disorders, such as Alzheimer's disease and other forms of dementia, is going up. To change that, we must work together, stay informed, and get involved. We are enrolling both people who have memory problems and people who are healthy and do not have memory problems.

Compensation: No
Ages: 18-110
Non-Oncology
Other
Skin Cancer - Melanoma

We are doing this study to find out if an investigational called Daromun (the study drug) is a safe and effective treatment for melanoma. We want to know if treating people with the drug before surgery to remove tumors can lower the chance of cancer recurrence.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Mental Health, Behavior, and Substance Abuse

We are doing this study to find out if combining psychological skills and a procedure called neurostimulation during one clinic session can help reduce negative emotions and problems with dealing with emotions in both a laboratory setting and in a person's everyday life.

Compensation: Yes
Ages: 18-55
Non-Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to find out if a drug called satralizumab (the study drug) is a safe and effective option for people with autoimmune encephalitis.

Compensation: Yes
Ages: 12-110
Non-Oncology
Duke University Hospital
Primary Brain and Spinal Cord Tumors

We are doing this study to find out if an investigational drug called NMS-0330593 (the study drug) is safe and effective option when it is given in combination with temozolomide (an approved drug for the treatment of diffuse glioma). We want to know if this drug combination works better than temozolomide on its own.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to collect information about the speeds of eye and head movements in healthy children and young adults. This information will help us establish normal values related to these movement speeds and patterns. If we have a measure of what is normal, this will help us determine the severity of symptoms or injury for people who are treated for concussions.

Compensation: Yes
Ages: 12-25
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Pickett Road Research, Other
Digestive System

We are doing this study to find out if an experimental drug called NST-6179 (the study drug) is a a safe and effective option for patients with intestinal failure-associated liver disease (IFALD).

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital