Clinical Trials Directory

404 clinical trials found.
Radiation Oncology

We are doing this study to find out if the study intervention (additional delayed MRI sequences) can tell the difference between radiation damage and tumor recurrence.

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital
Research for Healthy Adults

We are doing this study to learn how normal, healthy aging affects attention, perception, memory, and decision-making abilities. We also want to know which regions of the brain contribute to these abilities.

Compensation: Yes
Ages: 18-79
Non-Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to compare the effectiveness of atezolizumab + a multi-kinase inhibitor (either cabozantinib or lenvatinib) versus a multi-kinase inhibitor alone.

Compensation: No
Oncology
Heart and Circulation

We are doing this study to learn more about the differences in the muscle and blood of people that have Peripheral Arterial Disease (PAD).

Compensation: No
Non-Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib. We want to find out if adding gilteritinib to the usual treatment is beneficial for people with acute myeloid leukemia (AML).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare different experimental drug regimens to the usual treatment (cytarabine and daunorubicin) for acute myeloid leukemia (AML). We want to find out which options have the best outcomes. The different drug combinations we will be testing against the usual treatment are:

  • daunorubicin and cytarabine liposome
  • cytarabine and daunorubicin with venetoclax
  • azacitidine and venetoclax
  • daunorubicin and cytarabine liposome with venetoclax

Compensation: No
Ages: 18-59
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to see if blood and bone marrow samples can be tested in a timely manner that allows for the detection of certain markers that could guide cancer treatment.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Biobank / Biospecimen Collections

We are doing this study to better understand nonalcoholic fatty liver disease in people with HIV. We want to find out what are the most accurate, non-invasive diagnostic tests to detect scarring in the liver for people who have HIV. At this time, we do not have a good understanding of the following characteristics of steatotic liver disease in people with HIV:

  • Causes of the disease
  • Risk factors
  • The most accurate, non-invasive tests to measure liver scarring
  • How the disease progresses
  • Treatment options

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital