Clinical Trials Directory

437 clinical trials found.
Kidneys, Bladder and Urinary System

We are doing this study to keep tabs on the health status of people who have used, or who plan to use, a Medtronic® medical device to treat a urological or digestive disorder. This study is a registry, which means that it will allow us to compile information about how well these products work and how well they improve patients' quality of life.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Skin Cancer - Melanoma

We are doing this study to look at blood, tumor, and lymph node tissue from people with melanoma so we can improve diagnostic methods and therapies for people with melanoma.

Compensation: No
Oncology
Women's Health

We are doing this study to learn more about the symptoms of menopause in women with sickle cell disease (SCD). We want to learn more about how hydroxyurea, pain, and other SCD-related complications can affect their menopause experience. We hope this study can help us more quickly and easily find out when women with SCD might be experiencing health complications related to menopause.

Compensation: No
Ages: 35-110
Non-Oncology
Remote/online
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called bomedemstat (the study drug) for people with essential thrombocythemia who are unable to take hydroxyurea or do not get a benefit from it.

Compensation: No
Oncology
Head and Neck Cancer

We are doing this study to find the most effective, safe dose of an experimental drug called petosemtamab (the study drug). We also want to know how well it works compared to the standard treatments used for metastatic/recurrent head and neck squamous cell carcinoma (HNSCC).

Compensation: No
Oncology
Digestive System

We are doing this study to find out if an experimental drug called volixibat (the study drug) is a safe and effective option for itching that is caused by primary sclerosing cholangitis (PSC).

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Mental Health, Behavior, and Substance Abuse

We are doing this study to learn more about how well a study intervention works to reduce distress caused by misophonia. This intervention combines neurostimulation and skills-based training that is designed to help people think differently.

Compensation: Yes
Ages: 18-55
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called bomedemstat or hydroxyurea in people with essential thrombocythemia (ET). We also want to know which of these options works best for most people.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital