Clinical Trials Directory

392 clinical trials found.
Gynecologic Cancer

We are doing this study to find out if an experimental drug called MK-2870 (the study drug) is an option for patients with endometrial cancer. We want to know how well it works compared to standard chemotherapy.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called bomedemstat or hydroxyurea in people with essential thrombocythemia (ET). We also want to know which of these options works best for most people.

Compensation: No
Oncology
Primary Brain and Spinal Cord Tumors

We are doing this study to find out if giving patients a drug called atezolizumab before and after surgery for recurrent glioblastoma can improve how their cancer responds.

Compensation: No
Oncology

The purpose of this study is to better understand how prenatal maternal health, such as higher body mass, and well-being, such as mental health, are related to early child development. We are especially interested in identifying the factors that influence young children's ability to regulate their emotions. We hope that any new information we learn from this study could benefit young children in the years to come.

El propósito de este estudio es comprender mejor cómo la salud prenatal de la madre, como una mayor masa corporal, y el bienestar, como la salud mental, están relacionados con el desarrollo tempano de los niños. Estamos especialmente interesados en identificar los factores que influyen en la capacidad de los niños pequeños para regular sus emociones. Esperamos que cualquier información nueva que obtengamos de este estudio pueda beneficiar a los niños pequeños en los años venideros.

Compensation: No
Non-Oncology
Lifestyle, Fitness, Exercise, and Weight Management

We are doing this study to learn about how exercise benefits our health. We know that being physically active is good for us, but we do not completely understand how it changes the cells in our bodies to improve our health.

Compensation: No
Non-Oncology
Gastrointestinal Cancer

We are doing this study to see how tucatinib, trastuzumab, and mFOLFOX6 work to treat cancer of your colon or rectum that is HER2-positive with mFOLFOX6 alone or combined with bevacizumab.

Compensation: No
Oncology
Radiation Oncology

We are doing this study to find out if the study intervention (additional delayed MRI sequences) can tell the difference between radiation damage and tumor recurrence.

Compensation: No
Ages: 18-100
Oncology
Duke University Hospital
Research for Healthy Adults

We are doing this study to learn how normal, healthy aging affects attention, perception, memory, and decision-making abilities. We also want to know which regions of the brain contribute to these abilities.

Compensation: Yes
Ages: 18-79
Non-Oncology
Duke University Hospital