Clinical Trials Directory

We are doing this study to evaluate the outcomes of patellar instability treatments at Duke. We want to learn more about how people do over time after they have chosen surgical or non-surgical options for treatment. We want to evaluate several lifestyle factors after treatment, including return to activities, pain, or any need for additional treatment or surgery.

We are doing this study is to evaluate the outcomes of medial patellofemoral ligament (MPFL) reconstruction surgery. This surgery is a common treatment for recurrent patellofemoral instability. We want to find out what factors most influence the likelihood of this procedure being successful.

We are doing this study to find out if an experimental drug called KTX-1001 (the study drug) is a safe and effective treatment for multiple myeloma. We want to identify the most appropriate dose and dosing schedule of the study drug for patients with multiple myeloma.

We are doing this study to find out if a study drug called selinexor (also known as XPOVIO) is a safe and effective treatment for multiple myeloma when it is combined with other drugs.

We are doing this study to find the most effective, safe dose of an experimental drug called selinexor (the study drug). We want to know how well this study drug works in people with myelofibrosis when it is given in combination with a drug called ruxolitinib.

We are doing this study to find the most effective, safe dose of an experimental drug called selinexor (the study drug) for people with myelofibrosis (MF).

We are doing this study to compare a ketogenic diet (a diet with high fat, moderate protein, very low carbohydrate) versus a normal diet. We want to find out if it has any effect on survival time for people with glioblastoma multiforme (GBM). We also want to know how biomarkers change when people follow a ketogenic diet. A biomarker is a biological molecule found in blood, other body fluids, or tissues. Biomarkers may be a sign of a condition or disease and can be used to predict someone's response to a specific treatment.

We are doing this study to learn more about what causes glioblastoma (GBM), a type of brain cancer, and the factors that affect GBM patients' quality of life. This research will help us to understand why some people get GBM, including how their genes and health history may contribute to tumor development and progression.