Clinical Trials Directory

470 clinical trials found.
Research for Healthy Adults

We are doing this study to collect blood samples that may be used for the following:

  • To make sure equipment and assays are working properly
  • Staff training
  • Researching assay development (an assay is a laboratory test)

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to find out if an experimental drug called HLX43 (the study drug) is a safe and beneficial option for people with non-small cell lung cancer (NSCLC) that did not respond favorably to standard treatments.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Blood Disorders

We are doing this study to find out if an experimental drug called etavopivat (the study drug) is a safe and effective option for children and adolescents who have SCD.

Compensation: Yes
Ages: 12-17
Non-Oncology
Other
Other

We are doing this study to assess how accurately a medical device under test that can measure blood pressure and changes to blood pressure during surgery non-invasively. We want to compare its performance and accuracy to that of an arterial line, which is an invasive procedure.

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Immune System and Infections

Many people with HIV want to breastfeed their babies, but until recently, the rules in the U.S. didn't allow this. There's a small risk of passing HIV to the baby, but we need more information to understand this better. This research will make a list of babies and how they are fed, talk to families about why they choose certain ways to feed their babies, and test breast milk and blood to see if the HIV that can't be found in the blood is also not in the breast milk.

Compensation: Yes
Ages: 18-50
Non-Oncology
Duke University Hospital, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called abatacept (the study drug) is a safe and effective option to help prevent graft-versus-host (GVHD) disease for people who get an omidubicel hematopoietic stem cell transplant to treat blood cancer. Omidubicel is a recently approved (2023) stem cell transplantation that uses modified umbilical cord blood. This new method of stem cell transplantation helps patients' immune systems recover more quickly after intensive chemotherapy.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Complementary and Alternative Therapies

We are doing this study to learn if hyperbaric oxygen therapy is helpful to people with traumatic brain injury.

Compensation: No
Ages: 16-65
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find the most effective, safe dose of an experimental drug called P1101 (the study drug) in adults with early or low risk primary myelofibrosis (PMF).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital