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435 clinical trials found.
Bones, Joints and Muscles

We are doing this study to find out which type of surgery has the best outcomes for people who have shoulder dislocations with bone loss. There are 3 types of surgeries that doctors can perform to stabilize the shoulder of people who have this type of injury, but there is no evidence at this time that proves one is better than the others. We hope this study can help us figure out how to choose the best option for different patients. This is an observational study and participation will not affect the treatment option you choose to pursue.

Compensation: Yes
Ages: 18-50
Non-Oncology
Other
Eyes and Vision

We are doing this study to find out if an experimental gene transfer drug called OCU410ST is a safe and effective option for Stargardt Disease (STGD).

Compensation: Yes
Ages: 6-75
Non-Oncology
Duke University Hospital
Genitourinary Cancer

Compensation: No
Oncology
Head and Neck Cancer

We are doing this study to learn more about the olfactory receptor expression (which give us our sense of smell) and neurogenesis (creation of cells) in human olfactory tissue.

Compensation: No
Oncology
Breast Cancer

We are doing this study to improve how cancer patients and their providers communicate with each other. We want to know how personal biases can affect how cancer care is explained and managed. We think being able to identify bias if any exists can improve care and patients' psychological well-being.

Compensation: Yes
Ages: 21-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Infectious Diseases

We are doing this study to learn more about how genetics influence vulnerability and resistance to different types of infections.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Brain, Spinal Cord and Nerves

We are doing this study to compare activity in the brains of female adults who have chronic pain and/or use opioids to the brain activity of healthy female adults who are pain-free. We hope this study can help us develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

Compensation: Yes
Ages: 18-65
Non-Oncology
Duke University Hospital

We are doing this study to find out if non-opioid means of pain relief are adequate for children who need mechanical ventilation for the treatment of acute respiratory failure. We want to know if acetaminophen and/or ketorolac can help provide enough relief to lower the need for using opioids to treat pain. Opioid pain medications have side effects (e.g., withdrawal symptoms and delirium) that can potentially be lessened if the study drugs are shown to provide an acceptable benefit.

Compensation: No
Ages: 0-17
Duke University Hospital