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404 clinical trials found.
Blood Disorders

We are doing this study to learn more about the effects of the prescription drug Oxbryta (voxelotor) on sickle cell disease (SCD) when it is prescribed to patients. We want to keep track of the health of people with SCD who take this drug as part of their normal care.

Compensation: Yes
Ages: 12-110
Non-Oncology
Duke University Hospital
Breast Cancer

We are doing this study is to collect additional follow-up data and samples from participants who completed the P-RAD clinical trial.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Hematologic Malignancies and Cellular Therapy

We are doing this study to evaluate the performance of an experimental medical technology called the Patched Sepsis Prediction Algorithm (the study technology). This technology is designed to detect the early signs of sepsis and give clinicians the chance to treat it earlier than usual.

Compensation: No
Oncology
Immune System and Infections

If you choose to join this study, you or your child, will:

  • Allow us access to your medical record for up to 5 years
  • Answer questions about your health history and current symptoms
  • Have a nasal swab
  • Give a stool sample
  • Complete 3 follow-up phone calls
  • Have blood drawn (only if in the hospital or l)

Compensation: No
Non-Oncology
Research for Healthy Adults

We are doing this study to learn more about how certain vaccines can affect people's polyethylene glycol (PEG) sensitivity levels. PEG is a component of several different vaccines. We want to compare blood samples from healthy volunteers to blood samples from HIV Vaccine Trials Network (HVTN) 133 participants. We hope this will help us better understand the variation of PEG sensitivity in the general population and between vaccinated and unvaccinated individuals.

Compensation: Yes
Ages: 18-50
Non-Oncology
Other
Gastrointestinal Cancer

We are doing this study to find out if pelvic floor physical therapy can improve sexual function for women who have undergone pelvic radiation.

Compensation: No
Ages: 19-110
Oncology
Remote/online
Brain and Spine Metastasis

We are doing this study to see if the study drug, dostarlimab, can reduce the recurrence of cancer in people who have had their colon cancer surgically removed.

Compensation: No
Oncology
Radiation Oncology

We are doing this study to understand whether people who receive a lower radiation dose after an interim (the second scan) PET-CT identifies an early treatment response have a similar outcome to those receiving a standard radiation dose. The results of the interim PET-CT scan will be used to guide your radiation dose plan. Depending on the PET-CT results, you will either receive a reduced radiation dose or the standard radiation dose for your cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital