Directorio

We are doing this study to learn more about children with atrioventricular septal defect. We hope to improve care for patients with this condition in the future.

We are doing this study to find out if the combination of two drugs called nanatinostat and valganciclovir (the study drugs) are a safe and effective option for treating lymphoma in people who are EBV-positive. We will use different doses of the study drugs to determine what dose appears to be ideal for most people. The safety and effectiveness of nanatinostat on its own will also be tested in a small number of study participants.

We are doing this study to find out if breathing exercises can improve lung function for kids who have asthma.

We are doing this study to find out if giving a drug called Exparel (the study drug) as a spinal injection is a safe and effective option for pain management. The study drug is approved to treat pain after surgery and is injected into the surrounding area where the surgery was done. We want to know if the study drug can also be given as an intrathecal (into the space surrounding the spine) injection to help control pain.

If you decide to participate in this study, you will have a screening visit to see if you meet the criteria to be included in this study. If you are eligible, you will proceed to the study drug period. During this period, you will:

• Take the study drug tablets by mouth at about the same time each morning and within 30 minutes of finishing your breakfast for the first 15 days
• After the first 15 days, continue to take the study drug by mouth at approximately the same time every day, within 30 minutes of finishing a meal (breakfast, lunch, or dinner) of your choice

• Blood draws
• Imaging tests (CT, PET/CT and MRI)
• ECG

We are doing this study to find out if an experimental drug called STM-416 (the study drug) is a safe and effective option for patients with a history of high grade, non-muscle invasive bladder cancer (cancer only within the bladder) whose disease has returned and who require an operation to remove cancer from the bladder.

We are doing this study to find the most effective, safe dose of an experimental drug called disitamab vedotin (the study drug). We want to know how well this study drug works in people who have advanced or metastatic solid tumors.

We are doing this study to find out if the study drug, patritumab deruxtecan, can be measured in brain tumor tissue after a single dose is given before surgery to remove brain metastases.