Directorio

392 clinical trials found.
Heart and Circulation

We are doing this study to learn more about children with atrioventricular septal defect. We hope to improve care for patients with this condition in the future.

Compensation: No
Ages: 0-18
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if the combination of two drugs called nanatinostat and valganciclovir (the study drugs) are a safe and effective option for treating lymphoma in people who are EBV-positive. We will use different doses of the study drugs to determine what dose appears to be ideal for most people. The safety and effectiveness of nanatinostat on its own will also be tested in a small number of study participants.

Compensation: No
Oncology
Lungs and Breathing

We are doing this study to find out if breathing exercises can improve lung function for kids who have asthma.

Compensation: Yes
Ages: 6-17
Non-Oncology
Duke University Hospital
Research for Healthy Adults

We are doing this study to find out if giving a drug called Exparel (the study drug) as a spinal injection is a safe and effective option for pain management. The study drug is approved to treat pain after surgery and is injected into the surrounding area where the surgery was done. We want to know if the study drug can also be given as an intrathecal (into the space surrounding the spine) injection to help control pain.

Compensation: Yes
Ages: 18-50
Non-Oncology
Duke University Hospital, Other
Genitourinary Cancer

We are doing this study to find out if an experimental drug called STM-416 (the study drug) is a safe and effective option for patients with a history of high grade, non-muscle invasive bladder cancer (cancer only within the bladder) whose disease has returned and who require an operation to remove cancer from the bladder.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital

We are doing this study to find the most effective, safe dose of an experimental drug called talquetamab (the study drug) for people with relapsed/refractory multiple myeloma. We want to compare how the study drug works on its own to how it works in combination with different drugs.

Compensation: No
Gastrointestinal Cancer

We are doing this study to find out whether hepatic artery infusion (HAI) pump therapy with floxuridine and dexamethasone is an effective treatment for cholangiocarcinoma that cannot be removed with surgery and has not been treated yet. We want to find out whether the HAI pump treatment plus GemOx chemotherapy works as well as or better than GemOx alone at extending the time before your disease gets worse.

Compensation: No
Oncology
Phase I

We are doing this study to find the most effective, safe dose of an experimental drug called disitamab vedotin (the study drug). We want to know how well this study drug works in people who have advanced or metastatic solid tumors.

Compensation: No
Oncology