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We are doing this study to collect information about the speeds of eye and head movements in healthy children and young adults. This information will help us establish normal values related to these movement speeds and patterns. If we have a measure of what is normal, this will help us determine the severity of symptoms or injury for people who are treated for concussions.

We are doing this study to compare two commonly used treatment choices for early-stage breast cancer in premenopausal women. We want to know if either option is a better choice than the other.

We are doing this study to compare two surgical procedures. We want to know if one procedure is better than the other in terms of lowering the risk of developing ovarian cancer for pre-menopausal women with BRCA1 mutations.

We are doing this study to find out if a blood test for circulating tumor DNA (ctDNA) can provide information that might help doctors figure out the most appropriate therapy for patients with colon cancer after they have surgery.

We are doing this study to find out if an investigational drug called apalutamide (the study drug) is a safe and effective treatment for your form of cancer. We want to know how well people respond to the usual therapy (hormone therapy and radiation) in combination with the study drug compared to the usual therapy on its own.

We are doing this study to find out if 2 experimental treatments for high risk prostate cancer are effective compared to the usual treatments. For people with this form of cancer who also have a low gene risk score, we want to know if a short course of hormone treatment is as effective as the usual 24-month treatment. For people with a high gene risk score who will receive radiation, we want to know if adding a drug called apalutamide (study drug) to the usual treatment helps to slow the cancer's spread.

We are doing this study to learn more about using Decipher risk scores to guide how we treat cancer. During the study, we will test your tumor tissue for many different genes that all together indicate the risk of your cancer spreading. This is called the Decipher risk score.

This study will use Decipher risk scores as a guide for intensification (for higher Decipher gene risk) or de-intensification (for low Decipher gene risk) of treatment to better match therapies to an individual patient's cancer aggressiveness. We also want to know how well an investigational drug called darolutamide (the study drug) works for people with high risk scores.

We are doing this study to see if radiation and chemotherapy can be done instead of an extensive surgical removal of the groin lymph nodes for patients with vulvar cancer whose disease has spread to the sentinel node. We are doing this study because we want to find out if this approach is better or worse than the usual approach for vulvar cancer.