Directorio

392 clinical trials found.
Gastrointestinal Cancer

We are doing this study to compare the effectiveness of atezolizumab + a multi-kinase inhibitor (either cabozantinib or lenvatinib) versus a multi-kinase inhibitor alone.

Compensation: No
Oncology
Heart and Circulation

We are doing this study to learn more about the differences in the muscle and blood of people that have Peripheral Arterial Disease (PAD).

Compensation: No
Non-Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare the usual treatment of azacitidine and venetoclax to the combination treatment of azacitidine, venetoclax and gilteritinib. We want to find out if adding gilteritinib to the usual treatment is beneficial for people with acute myeloid leukemia (AML).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to compare different experimental drug regimens to the usual treatment (cytarabine and daunorubicin) for acute myeloid leukemia (AML). We want to find out which options have the best outcomes. The different drug combinations we will be testing against the usual treatment are:<ul>
<li>daunorubicin and cytarabine liposome</li>
<li>cytarabine and daunorubicin with venetoclax</li>
<li>azacitidine and venetoclax</li>
<li>daunorubicin and cytarabine liposome with venetoclax</li></ul>

Compensation: No
Ages: 18-59
Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to see if blood and bone marrow samples can be tested in a timely manner that allows for the detection of certain markers that could guide cancer treatment.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Biobank / Biospecimen Collections

We are doing this study to better understand nonalcoholic fatty liver disease in people with HIV. We want to find out what are the most accurate, non-invasive diagnostic tests to detect scarring in the liver for people who have HIV. At this time, we do not have a good understanding of the following characteristics of steatotic liver disease in people with HIV:<ul>
<li>Causes of the disease</li>
<li>Risk factors</li>
<li>The most accurate, non-invasive tests to measure liver scarring</li>
<li>How the disease progresses</li>
<li>Treatment options</li></ul>

Compensation: Yes
Ages: 18-110
Non-Oncology
Duke University Hospital
Research for Healthy Adults

We are doing this study to find out if an investigational vaccine (HydroVax-005 CHIKV - the study vaccine) is a safe and effective option to protect against chikungunya virus. Chikungunya virus is spread by mosquitos that are most common in Africa, Asia, and India. Infection with the virus can cause serious disease in older adults, children, and people with weaker immune systems.

Compensation: Yes
Ages: 18-49
Non-Oncology
Other
COVID-19

We are doing this study to learn more about changes in nasal tissue in people that have COVID-19.

Many COVID-19 patients have reported a change in sense of smell and we would like to find out why that is.

Compensation: No
Non-Oncology