Clinical Trials Directory
We are doing this study to find out if a drug called fluoxetine (the study drug) can cause changes to structures in your cells called lysosomes that then improve how well the chemotherapy drug temozolomide (TMZ) kills cancer cells in the brain. Lysosomes are organelles (structures in cells) that contain digestive enzymes (substances that break down chemicals) that help keep the cells free of extra or worn out cell parts. The study drug is approved by the FDA to treat problems like depression and anxiety, but we do not know if it also might be beneficial in treating cancer.
We are doing this study to find out if surgically removing only the cancerous lymph node (known as a lymph node excision) is effective at preventing melanoma from coming back in the same area of the lymph node excision. We also want to learn more about the side effects of this type of surgery and how it can impact patients' quality of life.
We are doing this study to learn more about a medical technology called the ExoDx Prostate test. We want to find out if these test results can help us evaluate the risk of prostate cancer for patients and make better informed clinical decisions.
We are doing this study to examine genetic changes in your tumor that may contribute to resistance to immunotherapy. With this information, we hope to be able to identify new treatment methods as well as improve our ability to identify patients more likely to respond to immunotherapy.
We are doing this study to find out if the experimental combination of the drugs finalimab and cemiplimab (the study drugs) is a safe and effective option for people with high-risk melanoma. We want to see how well the study drugs work compared to treatment with pembrolizumab.
We are doing this study to test a new intervention that is designed to help adolescents and young adults who have signs and symptoms of an eating disorder. This study is funded by a grant from the National Institute of Mental Health.
We are doing this study to understand more about biomarkers (a part of your body) and how they can be used to better diagnose infection.
To learn more, please contact us at DukeMESSIStudy@Duke.edu or at 919-452-1605.
Estamos haciendo este estudio para entender más sobre biomarcadores (que son parte de su cuerpo) y cómo pueden ser usados estos para diagnosticar infecciones de una mejor manera.
Para mayor información, por favor contáctenos al correo DukeMESSIStudy@Duke.edu o al número 919-452-1605.
We are doing this study to learn more about the cause of cardiac (heart) disease or sudden unexplained death, which is something that can run in families.
Some conditions that we are looking at are:<ul>
<li>Cardiomyopathies (a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body) like hypertrophic cardiomyopathy, dilated cardiomyopathy, or arrhythmogenic right ventricular cardiomyopathy</li>
<li>Arrhythmia syndromes (a problem with the rate or rhythm of the heartbeat, either too slow or too fast) like long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, or short QT syndrome</li>
<li>Sudden cardiac arrest or unexplained sudden death (heart stops suddenly), including sudden infant death syndrome (SIDS)</li></ul>