Clinical Trials Directory

593 clinical trials found.
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called CAP-100 (study drug) is a safe and effective treatment for people who have CLL or SLL that is not responding to standard treatments. We also want to know what dose of this study drug works best.

Compensation: No
Oncology

If people join this study, they will be placed into one of two groups by chance. Everyone will receive a computer based treatment designed to help them stop using cannabis. The treatment includes seven sessions, and a study team member will call each week to provide support and check on progress. Some participants will also receive an extra program called mobile contingency management. In this program, participants will record themselves taking saliva tests and upload the videos to the study website. If the tests show they have not used cannabis, they can earn money as a reward. After the treatment period, participants will complete five follow up sessions. Researchers want to learn which approach works best to help people stop using cannabis and maintain their progress over time.

Compensation: Yes
Ages: 18-110
Remote/online
Infectious Diseases

Compensation: No
Non-Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to monitor the health and quality of life of people who participated in clinical trials for GM T cell therapies.

Compensation: No
Oncology
Brain, Spinal Cord and Nerves

We are doing this study to find out if an experimental cell therapy called NRTX-1001 (the study drug) is a safe and effective treatment for drug-resistant mesial temporal lobe epilepsy (MTLE). We want to know if the study drug can reduce seizures in people who are not getting relief from conventional treatments.

Compensation: Yes
Ages: 18-65
Non-Oncology
Duke University Hospital
Heart and Circulation

In this study, you will have a heart procedure called an ablation using a special system called the nsPFA Cardiac Surgery System. After the procedure, you will have follow up visits at one month, three months, six months, and twelve months. Around each visit, you will wear a heart monitor to track your heart rhythm and use a phone app to share information. The study team will also collect information about your medicines and your health during the study.

Compensation: Yes
Ages: 18-85
Non-Oncology
Duke University Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called cema-cel is a safe and effective option for patients with large B-cell lymphoma. Cema-cel is a CAR T Cell therapy that is made from your own white blood cells. We also want to compare how well cema-cel works when it is given with and without another experimental drug called ALLO-647.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Remote

We are doing this study to learn more about the needs and challenges of Black parents and caregivers who are taking care of children who have special healthcare needs. We want to be able to provide better support for these families in the future.

Compensation: Yes
Ages: 18-110
Non-Oncology
Remote/online