Clinical Trials Directory

392 clinical trials found.

We are doing this study to learn how to best support young women making decisions about breast cancer surgery. We want to know what makes women feel uncertain about their decision-making so we can become better at providing the information they need. This study involves testing a web-based decision support tool that is designed to help young women with newly diagnosed breast cancer with their surgical decisions.

Compensation: Yes
Ages: 18-44
Remote/online
Breast Cancer

We are doing this study to find out if the use of continuous glucose monitors (CGMs) is worthwhile to help breast cancer patients and their providers monitor for hyperglycemia, or high blood sugar, during chemotherapy. A CGM is a small, wearable sensor that is attached to the skin to frequently measure your blood sugar level, and can share the measurements to your smartphone and to your medical team.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital
Gynecologic Cancer

We are doing this study to see whether programs are helpful for couples where one partner has cancer.

Compensation: Yes
Ages: 18-80
Oncology
Remote/online
Research for Children and Teenagers

We are doing this study to learn more about the immune response patients with X-linked Agammaglobulinemia (XLA) have to COVID-19 vaccination. We will compare their immune responses to those of healthy people who have normal immune systems. Better understanding of cellular responses to COVID-19 vaccines by XLA patients is important since XLA patients cannot make antibodies to vaccines.

If you are interested, please contact the study team at XLACOVIDvax@duke.edu.

Compensation: No
Non-Oncology
Breast Cancer

We are doing this study to better understand how breast cancer treatment can affect the heart. In particular, we want to know if treatment with near complete estrogen deprivation (NCED) therapy has an impact on heart function.

Compensation: Yes
Ages: 18-55
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Cancer Immunotherapy

We are doing this study to find out if an experimental drug called CTX131 (the study drug) is a safe and effective treatment for different forms of cancer with solid tumors. The study drug is made from white blood cells or T cells from healthy donors.

Compensation: No
Oncology
Gynecologic Cancer

We are doing this study to find out if using ice with or without compression during chemotherapy can prevent neuropathy for patients being treated for gynecologic cancer.

Compensation: No
Ages: 19-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Heart and Circulation

We are doing this study to find out if an experimental product called cryopreserved platelets (CPP) can help control the bleeding that happens during and after cardiopulmonary bypass surgery. We want to see how well this product works in comparison to the standard therapy that is used to control bleeding during surgery, which is liquid stored platelets (LSP).

Compensation: No
Non-Oncology