Directorio

We are doing this study to determine the safety and effectiveness of an experimental medical device called the GORE Ascending Stent Graft (ASG Device) for the treatment of aortic diseases.

This study is comparing two chemotherapy treatment plans for children and young adults with newly diagnosed intermediate risk rhabdomyosarcoma. Researchers want to learn whether a higher dose treatment given over a shorter time works as well as or better than a lower dose treatment with additional maintenance therapy given over a longer time, along with standard surgery and radiation.

Participants in this study will take a medicine called acoramidis by mouth two times each day for about three years. The study includes a screening period, a treatment period, and a follow up period after treatment ends. During the study, participants will have regular visits so doctors can monitor their heart health and overall well being. Researchers want to learn more about the long term effects of acoramidis in people with transthyretin amyloid cardiomyopathy, a disease caused by abnormal protein buildup in the heart. The goal is to see how well the medicine works over time and how safe it is for patients.

We are doing this study to find out if a study drug called sacituzumab govitecan can improve outcomes for patients with high risk, early triple negative breast cancer (TNBC). We want to know if giving this drug in combination with pembrolizumab will work better than pembrolizumab on its own or better than pembrolizumab + capecitabine.

We are doing this study to find out if an experimental drug called asciminib (the study drug) is a safe and effective option for people with metastatic HER2+ breast cancer with brain metastases when it is combined with trastuzumab.

We are doing this study to find out if an experimental drug called ASP2138 (the study drug) is a safe and effective option for people who have pancreatic cancer that can be treated with surgery. We want to know if the study drug has a benefit when it is taken by patients before their surgery who then have standard chemotherapy after their surgery.