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456 clinical trials found.
Lungs and Breathing

We are doing this study to determine the impact of smoking electronic cigarettes (e-cigs) on lung health. This will be done by comparing study procedures and imaging results between healthy participants that use e-cigs versus those who don't.

Compensation: Yes
Ages: 18-35
Non-Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to compare the performance of 2 drugs: zanzalintinib and everolimus. We want to know which option is the most effective for treating neuroendocrine tumors.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called XTX101 (the study drug) is a safe and effective option for people who have advanced tumors or metastatic microsatellite stable colorectal cancer. We want to see how well it works on its own and in combination with a drug called atezolizumab.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Transplant Medicine

People in this study will still get their regular medical care. The study is only about trying a special kind of liver transplant using a machine called Liver Assist to help keep the liver healthy. The liver must come from a donor and meet certain rules. People can still wait for a regular liver transplant outside the study. Doctors will collect information from their medical records to learn how they’re doing and how the surgery goes.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this study to find out if Non-Ischemic Heart Preservation using an experimental technology called the XVIVO Heart Preservation System (the study technology) is a safe and effective way to preserve extended criteria donor hearts that can be transplanted into patients who need a donor heart. The study technology is designed to preserve donor hearts using a device with a temperature-controlled perfusion solution that flows through the heart during transport. We want to know if this can allow donor hearts to travel a greater distance to patients who are awaiting a transplant.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to find the safest and most effective dose of an experimental drug called ZL-1310 (the study drug). We want to know if this drug can be beneficial for people with small cell lung cancer (SCLC) that progressed after at least one round of chemotherapy.

Compensation: No
Oncology
Breast Cancer

We are doing this study to find out if an experimental drug called zelenectide pevedotin (the study drug) is a safe and effective option for people with breast cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Gastrointestinal Cancer

We are doing this study to find out if a drug called zolbetuximab, when it is combined with pembrolizumab and standard chemotherapy, is a safe and effective option for treating stomach cancer.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital