Clinical Trials Directory

404 clinical trials found.
Older Adults/Aging

We are doing this study to help us identify the underlying causes of brain disorders such as delirium and/or dementia.

Compensation: Yes
Ages: 65-110
Non-Oncology
Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital
Brain and Spine Metastasis

We are doing this study to find out if a new experimental drug called NVL-655 (the study drug) is a beneficial option for people with NSCLC.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to learn more about the side effects of the study drug and to determine if it will help shrink the cancer by at least 30%.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Thoracic Cancer

We are doing this study to research the genes of patients with lung cancer that has been or will be removed by surgery for a chance to get treatment in a clinical trial.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital, Other
Eyes and Vision

We are doing this study to find out if an investigational gene therapy drug called ABBV-RGX-314 (the study drug) is a safe and effective option for people with diabetic retinopathy. The study drug is delivered directly into the suprachoroidal space of the eye using a technology called Microinjector®, which is an experimental needle device.

Compensation: Yes
Ages: 25-89
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to learn if a new study drug called AMG-509 is safe and effective in men who have metastatic, castrate-resistant prostate cancer. AMG-509 is a type of drug that helps a type of immune cells called T cells find and kill prostate cancer cells. The first part of this study will test different doses of AMG-509 in men to learn what side effects the study drug causes and which doses are safe. The second part of the study will see if a safe dose of AMG-509 slows cancer growth. This study will also teach us how long AMG-509 stays in your body, and whether treatment with AMG-509 changes the genes and proteins found in your tumor cells.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

We are doing this study to find out how an experimental drug called sotorasib works in your body and against your cancer. We will compare how this drug works alone and in combination with several different drugs.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Gastrointestinal Cancer

We are doing this study to compare how safe and effective different drug combinations are for treating metastatic cancer.

Compensation: No
Oncology