Clinical Trials Directory

Our Duke Vaccine and Trials Unit Volunteer Registry is a way for people to let our team know that you are interested in learning more about any of our vaccine studies you may be interested in. For more information or to sign up, visit us at: https://redcap.duke.edu/redcap/surveys/?s=WC8MR9PLMN Nuestro Registro Voluntario de la Unidad de Vacunas y Ensayos Clínicos de Duke es el medio a través del cual las personas pueden hacerle saber a nuestro equipo que están interesados en conocer más sobre nuestros estudios de investigación en los cuales podrían participar. Para más información o para registrarse, visítenos en: https://redcap.duke.edu/redcap/surveys/?s=WC8MR9PLMN

Our Duke Health and Exercise Research Trials Registry is a way for people to let our team know that they are interested in learning more about any of our studies for which they may qualify. Our studies include both healthy people and those who may have certain medical conditions.

We created the Duke Clinical Research Volunteer Registry for people who would like to join clinical research studies. We will use this registry to contact you about available studies. For more information or to sign up, visit us at: https://redcap.duke.edu/redcap/surveys/?s=X4T7JKHPX4

We are doing this study to look at components of the blood to see if there are features that distinguish people with dystonia from people without dystonia. Identifying "biomarkers" in the blood that are associated with dystonia is greatly needed to help more accurately diagnosis dystonia and to identify subsets of dystonias that may have shared mechanisms. Being able to group individuals by underlying mechanisms can guide people with dystonia to the most appropriate future treatments that act specifically to correct one cause or another.

The Endometrial Cancer Molecularly Targeted Therapy Consortium is a multi-institutional alliance that is developing a cancer data and tissue repository. The information in this repository will be used to better understand tumor alterations and cancer biomarkers that can help us develop new therapies and potentially improve survival outcomes for women with endometrial cancer.

We are doing this study to learn more about the cause of cardiac (heart) disease or sudden unexplained death, which is something that can run in families. Some conditions that we are looking at are:

• Cardiomyopathies (a disease of the heart muscle that makes it harder for your heart to pump blood to the rest of your body) like hypertrophic cardiomyopathy, dilated cardiomyopathy, or arrhythmogenic cardiomyopathy (also called right ventricular cardiomyopathy)
• Arrhythmia syndromes (a problem with the rate or rhythm of the heartbeat, either too slow or too fast) like long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, or short QT syndrome
• Sudden cardiac arrest or unexplained sudden death (heart stops suddenly) in someone less than 50 years of age, including sudden infant death syndrome (SIDS)
• Individuals with genetic mutations (variants) in genes that can lead to cardiac disease which include (LMNA, ATP1A3, and TAX1BP3)

We are doing this study to collect blood samples that may be used for the following:

• To make sure equipment and assays are working properly
• Staff training
• Researching assay development (an assay is a laboratory test)

If you agree to be in the study, you will have 1 study visit that will last about 4 hours. The visit will include asking questions about your medical history, vital signs, pulmonary function tests (PFTs) and an MRI (magnetic resonance image) of the chest with inhaled Xenon gas. Someone from the study team will contact you about 24 hours after your study visit.