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605 clinical trials found.
Hepatology

Compensation: No
Non-Oncology
Lungs and Breathing

We are doing this study to find out if an investigational drug called tocilizumab (the study drug) will lead to better outcomes after lung transplantation when it is combined with standard anti-rejection medicines.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital
Heart and Circulation

We are doing this research to learn more about whether taking a blood thinner, along with medications that prevent blood clots, improve outcomes in patients who develop atrial fibrillation (irregular heartbeat) after coronary artery bypass grafting surgery.

Compensation: No
Ages: 18-110
Non-Oncology
Duke University Hospital, Duke Regional Hospital
Eyes and Vision

Participants will receive the study drug in one eye during an outpatient surgery and will not need to stay in the hospital. Participation will last about 5 years and 5 months and includes 17 study visits, 1 phone visit, and regular tests and eye examinations.

Compensation: Yes
Ages: 55-110
Non-Oncology
Duke University Hospital

This study is for breastfeeding women who are taking certain medicines as part of their regular medical care and for their breastfed babies. Participants may choose to provide samples of breast milk, blood from the mother, and blood from the baby. Researchers will use these samples to learn how these medicines move into breast milk and how much of the medicine may reach the baby during breastfeeding. The goal is to help doctors better understand the safety of these medicines for breastfeeding families.

Compensation: Yes
Ages: 0-110
Duke University Hospital, Duke Regional Hospital
Primary Brain and Spinal Cord Tumors

We are doing this study to find out if an investigational drug called CA-4948 is a safe and effective option for people with PCNSL. We want to know how well it works when it is combined with a drug called ibrutinib, which is commonly used to treat PCNSL.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital

This study is testing a new way to guide a brain stimulation tool called TMS by using a camera to track a person's head. The goal is to do this without needing special headgear. Researchers hope this new method will make the treatment more comfortable and easier for people. They also want to see if it helps aim the tool more accurately, which could improve how well the treatment works.

Compensation: Yes
Ages: 18-110
Duke University Hospital