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478 clinical trials found.
Research for Children and Teenagers

We are building a database of people who would like to be contacted about future dermatology research studies. This is a way for people who are interested in participating in research opportunities to learn about a research study that they may not have otherwise known about.

Compensation: No
Ages: 0-110
Non-Oncology
Remote/online
Primary Brain and Spinal Cord Tumors

We are doing this study to test the safety and effectiveness of the study drug, datopotamab deruxtecan (also known as dato-DXd), and find out if it is a potential option for patients with metastatic breast cancer that has spread to the brain and/or spinal cord.

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Brain, Spinal Cord and Nerves

Compensation: No
Non-Oncology
Brain, Spinal Cord and Nerves

We are doing this study to find out if an investigational drug called iptacopan (the study drug) is safe and has beneficial effects for people who have generalized Myasthenia Gravis (gMG).

Compensation: Yes
Ages: 18-75
Non-Oncology
Duke University Hospital

This study will last about 35 weeks and has three parts: Screening, Dosing, and Follow-up. It is a double-blind study, which means neither you nor the doctors will know if you get the real medicine or a placebo. The medicine or placebo will be given as two shots under the skin. After you agree to join, treatment will start. There will be phone calls at weeks 3, 5, 7, 9, and 11 to check on your medicine and any side effects. You will have regular health checkups, physical exams, and tests like ECGs to check your heart. You will also answer short surveys about your symptoms, energy, mood, and work. You will come back at 3, 6, and 12 months for blood tests. Over the whole study, about one cup of blood will be taken. These tests will check your health, medicine levels, antibodies, and screen for diseases like HIV, hepatitis, and tuberculosis.

Compensation: Yes
Ages: 18-75
Duke University Hospital
Immunology and Rheumatology

We are doing this study to find out if an experimental drug called CABA-201 (the study drug) is a safe and effective option for people with systemic sclerosis.

Compensation: Yes
Ages: 18-75
Non-Oncology
Duke University Hospital
Brain and Spine Metastasis

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital
Brain and Spine Metastasis

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital