REALISE

REALISE

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Purpose of this Study

This study lasts for about one and a half months. People will go to the doctor up to six times in person and have one phone call visit. The first visit will take about four and a half hours and will include a brain scan and tests to see how well someone can do certain tasks. This long visit can be split into two shorter visits if that is easier. After that, there will be three visits where people get a special kind of treatment, and each of those visits will take about an hour and a half.

Who Can Participate?

Eligibility

This study is for people who are at least 21 years old. They must have had their first stroke at least three months ago. The stroke could have been caused by a blocked blood vessel or bleeding in the brain. They must have weakness in one arm. Doctors will also check how the muscles in their hand respond to signals to see if they can be part of the study.

Age Range

21-110

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No

What is Involved?

Description

The purpose of this study is to see how a treatment called TMS can help people move their arms better. TMS stands for transcranial magnetic stimulation. It uses magnets to help the brain work in a different way. TMS is already approved to help people with depression, and doctors have also looked at how it helps people after a stroke. But scientists still need to learn the best way to use it to help people recover.

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

Evaluation of 3 patterned rTMS stimulation dosage on corticospinal excitability and motor learning in stroke patients

Principal Investigator

Wuwei
Feng

Protocol Number

PRO00117160

NCT ID

NCT06765642

Phase

N/A

Enrollment Status

Open to Enrollment