Purpose of this Study
We are doing this study to find out if giving patients a drug called atezolizumab before and after surgery for recurrent glioblastoma can improve how their cancer responds.
Who Can Participate?
Eligibility
Adults ages 18+ who:
- Are diagnosed with glioblastoma (isocitrate dehydrogenase wildtype)
- Have a recurrence after treatment with radiation and temozolomide
- Plan to have surgery
What is Involved?
Description
If you join the study, you will:
- Have a physical exam and other tests
- Have magnetic resonance imaging (MRI) scans of the brain
- Have blood draws
- Get atezolizumab before surgery
- Get atezolizumab after surgery
Study Details
Full Title
A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial
Principal Investigator
Mustafa
Khasraw
Protocol Number
PRO00113395
NCT ID
NCT06069726
Phase
N/A
Enrollment Status
Open to Enrollment