If you choose to join the study, it will involve following an assigned diet for 18 weeks, a follow-up with our team at 18-months after the diet ends, and a follow-up with the study team every year for the next 3 years. Before beginning the 18 weeks of the diet, you will get a random assignment (like a coin flip) to 1 of 2 diets:

• A ketogenic diet; OR
• A usual diet following the American Cancer Society Guidelines of Diet and Physical Activity

During the 18 weeks of the diet you will:

• Have weekly or bi-weekly meetings with a dietitian
• Have blood draws and give stool samples
• Have imaging scans (MRI)
• Wear a Fitbit device to continuously monitor your physical activity and sleep
• Weigh yourself weekly
• Use an at home Keto-Mojo device daily to collect a drop of blood and monitor your ketone and glucose levels (this only applies to people assigned to follow a ketogenic diet)

About 7 days after you finish the study diet, you will have an end-of-study visit to see how you are doing. At that visit you will:

• Meet with a dietitian
• Have blood draws and give a stool sample
• Have an imaging scan (MRI)
• Provide a final drop of blood to measure your ketone and glucose levels (participants assigned to the ketogenic diet only)

About 18 months after that visit, someone from the study team will contact you to see how you are doing. Your doctor will continue to follow your condition every year for the next 3 years. Your doctor may do this by a phone call or by reviewing your medical records.