Clinical Trials Directory

We created the Registry for Brain Health to help you improve your brain health and get involved in research studies. The number of people in North Carolina affected by memory disorders, such as Alzheimer's disease and other forms of dementia, is going up. To change that, we must work together, stay informed, and get involved. We are enrolling both people who have memory problems and people who are healthy and do not have memory problems.

We are doing this study to learn more about the rare diagnosis of New Daily Persistent Headache (NDPH). We want to get more information about why some children and young people develop this condition and how it is different from traditional headaches, like migraines. This knowledge can help us to begin developing possible treatments for NDPH.

We are doing this study to collect information about the speeds of eye and head movements in healthy children and young adults. This information will help us establish normal values related to these movement speeds and patterns. If we have a measure of what is normal, this will help us determine the severity of symptoms or injury for people who are treated for concussions.

We are doing this study to learn more about how genetics influence vulnerability and resistance to different types of infections.

We are doing this study to compare activity in the brains of female adults who have chronic pain and/or use opioids to the brain activity of healthy female adults who are pain-free. We hope this study can help us develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

We are doing this study to learn more about how certain vaccines can affect people's polyethylene glycol (PEG) sensitivity levels. PEG is a component of several different vaccines. We want to compare blood samples from healthy volunteers to blood samples from HIV Vaccine Trials Network (HVTN) 133 participants. We hope this will help us better understand the variation of PEG sensitivity in the general population and between vaccinated and unvaccinated individuals.

We are doing this study to find out if we can identify biomarkers that indicate the presence of ovarian cancer or indicate that it is likely to develop. Biomarkers are substances that can be released from cancer cells into the blood and can provide information on the following things: changes to someone's genes or DNA, how cancer cells will respond to cancer treatment, and whether cells are becoming resistant (no longer responding) to cancer treatment.

We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease. *The study drug is a statin, which is usually used to help lower cholesterol levels.