Clinical Trials Directory
Everyone who joins this study will take a medicine called ribociclib by mouth once a day for 21 days, then have a 7-day break. This makes a 28-day cycle. They will also take hormone therapy (endocrine therapy) every day. This treatment will last for about 3 years (around 39 cycles). After finishing treatment or stopping early, patients will have a visit called End of Treatment and then a safety check 30 days later. After that, doctors will keep track of their health and survival for a long time—up to 4 years after the last person starts treatment.
People in this study will be placed into two groups. One group will take three medicines, and the other group will take two medicines and a fake pill. All pills are taken by mouth. At first, visits happen every week, then every month. Some visits may take a long time. The study has different parts and can last up to 5 years, depending on how well the treatment works.
If you join this study, your care will be similar to the usual treatment for an abdominal aortic aneurysm. You will still receive the scans, visits, and treatments you need. The main difference is that your treatment plan will be decided by chance. Some people may have surgery earlier, depending on their group. You will also be asked to fill out questionnaires and allow the study team to collect information from your medical records or Medicare. Taking part in the study will last about five years and will include one or two in person visits and a few follow up contacts by phone or video.
We are doing this study to develop an algorithm to help make accurate decisions about how to manage traumatic wounds. We hope this tool will help us determine the ideal time to use surgery to close major wounds in a way that will best promote healing.
We are doing this study to find out if an experimental drug and device system called X-PACT is a safe and effective treatment for various forms of cancer.
If you join the study, doctors will place a small tube made from a man made material into your arm using normal surgery methods. You will also need to come to many study visits. These will happen at the beginning, on the day of the procedure, when you leave the hospital, and at 1, 3, 6, 12, 18, 24, 36, 48, and 60 months after the procedure.
We are doing this study to find out if an experimental drug called XmAb819 (the study drug) is a safe and effective treatment for clear cell renal cell carcinoma (ccRCC).
We are doing this study to determine the impact of smoking electronic cigarettes (e-cigs) on lung health. This will be done by comparing study procedures and imaging results between healthy participants that use e-cigs versus those who don't.