Purpose of this Study
We are doing this study to find out if an inspiratory muscle training (IMT) program is beneficial for people with LOPD. We want to know if IMT can help reduce the effects of weakness in breathing muscles and improve the quality of life for people with LOPD.
Who Can Participate?
Eligibility
Adults ages 18+ who:
- Are diagnosed with LOPD
- Have access to a computer or tablet, a smartphone, and a reliable internet connection
For more information about this study, please contact the study team at Kelly.Crisp@duke.edu.
- Are diagnosed with LOPD
- Have access to a computer or tablet, a smartphone, and a reliable internet connection
For more information about this study, please contact the study team at Kelly.Crisp@duke.edu.
Age Range
18-110
Sex/Genders
Male (cisgender)
Female (cisgender)
Looking for Healthy Participants
No
What is Involved?
If you choose to join this study, you will:
- Use a device called PrO2 to complete your IMT program
- Do exercises according to your IMT program 3 times per week
The study's IMT program lasts for about 6 months. The PrO2 device you use in this study will share your training results with our staff. We might use this information to make changes to your exercise program while you are in the study.
- Use a device called PrO2 to complete your IMT program
- Do exercises according to your IMT program 3 times per week
The study's IMT program lasts for about 6 months. The PrO2 device you use in this study will share your training results with our staff. We might use this information to make changes to your exercise program while you are in the study.
Locations
Remote/online
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
High-dose inspiratory muscle training (IMT) in late-onset Pompe disease (LOPD)
Principal Investigator
Harrison
Jones
Protocol Number
PRO00109392
NCT ID
NCT05431127
Phase
N/A
Enrollment Status
OPEN TO ACCRUAL