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What happens during the study? - You'll get the study medicine through an IV every 3 weeks - Doctors will take blood and urine samples - You'll have regular CT or MRI scans to check your health

This study lasts for 90 days. People who join will wear a cloth cap with special sensors on their head. A computer will help decide which group they are in. Some people will get a real treatment, and others will be in a control group, which means they do not get the real treatment. After each of the one, two, or three treatment sessions, people will answer ten questions about how they feel. A doctor or helper will also check how their brain and body are working for five minutes. One day after the treatment, they will get a brain scan and a test to see how blood moves in their brain. They will also have short check-ups in person on day one and day four, a phone call on day thirty, and another in-person visit on day ninety.

We are doing this study to understand how different factors, such as pain experiences and inflammation, may affect how acute back pain transitions to chronic back pain.

We are doing this study to find the most effective, safe dose of an experimental drug called iadademstat (the study drug). We want to know if the study drug is beneficial for people with R/R AML that have the FLT3 mutation when it is given in combination with gilteritinib.

We want to compare two ways to help older adults check their blood pressure at home. One way includes help from a pharmacist, and the other does not. We want to see which way works better for lowering blood pressure in people who have more than one health problem.

If you join this study, you will be randomly placed into one of two groups - one group will get the study medicine, and the other will get a placebo, which is a fake medicine. You will give yourself a shot once a week. The amount of medicine in the shot will go up every 4 weeks, starting at a small dose and going up to a bigger dose. The study may last up to 12 months. During that time, doctors will check your health with tests like: - Measuring your height, weight, and vital signs - Taking blood samples - Doing pregnancy tests - Doing a spinal tap at the beginning and end of the study - Eye exams - Brain and nerve check-ups - Surgery check-ups - Help with nutrition, exercise, and healthy habits - Keeping a diary about headaches and medicine - Answering questions in surveys