PREVENTABLE (Dementia Prevention in Older Adults)

PREVENTABLE (Dementia Prevention in Older Adults)

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Purpose of this Study

We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease. *The study drug is a statin, which is usually used to help lower cholesterol levels.

Who Can Participate?

Eligibility

Adults ages 75+ who:
  • Do not currently take a statin
  • Do not have heart disease
  • Do not have dementia
  • Are able to perform everyday activities
For more information, please contact the study team at DukePREVENTABLE@duke.edu.

Age Range

75-110

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes

What is Involved?

Description

If you choose to join this study, you willd get a random assignment (like a coin flip) to 1 of 2 groups:
  • Group 1 will take the study drug daily (Atorvastatin)
  • Group 2 will take a placebo daily (harmless pill that does nothing)
All participants will:
  • Give a blood sample
  • Complete memory tests
  • Complete physical tests
*This study will last 5 years. If you are interested, you have the choice of participating in either Durham, NC or Kannapolis, NC.

Locations

Pickett Road Research
Kannapolis
Other

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

Yes

Study Details

Full Title

PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults (All Site sIRB)

Principal Investigator

Ranee
Chatterjee Montgomery

Protocol Number

PRO00103930

NCT ID

NCT04262206

Phase

IV

Enrollment Status

Open to Enrollment