Purpose of this Study
We are doing this study to find out if taking the study drug (Atorvastatin) can help older adults live longer and healthier by preventing dementia, disability, or heart disease.
*The study drug is a statin, which is usually used to help lower cholesterol levels.
*The study drug is a statin, which is usually used to help lower cholesterol levels.
Who Can Participate?
Eligibility
Adults ages 75+ who:<ul>
<li>Do not currently take a statin</li>
<li>Do not have heart disease</li>
<li>Do not have dementia</li>
<li>Are able to perform everyday activities</li></ul>
For more information, please contact the study team at <a href= "mailto: DukePREVENTABLE@duke.edu">DukePREVENTABLE@duke.edu.</a>
<li>Do not currently take a statin</li>
<li>Do not have heart disease</li>
<li>Do not have dementia</li>
<li>Are able to perform everyday activities</li></ul>
For more information, please contact the study team at <a href= "mailto: DukePREVENTABLE@duke.edu">DukePREVENTABLE@duke.edu.</a>
Age Range
75-110
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes
What is Involved?
If you choose to join this study, you willd get a random assignment (like a coin flip) to 1 of 2 groups:<ul>
<li>Group 1 will take the study drug daily (Atorvastatin)</li>
<li>Group 2 will take a placebo daily (harmless pill that does nothing)</li></ul>
All participants will:<ul>
<li>Give a blood sample</li>
<li>Complete memory tests</li>
<li>Complete physical tests</li></ul>
*This study will last 5 years.
If you are interested, you have the choice of participating in either Durham, NC or Kannapolis, NC.
<li>Group 1 will take the study drug daily (Atorvastatin)</li>
<li>Group 2 will take a placebo daily (harmless pill that does nothing)</li></ul>
All participants will:<ul>
<li>Give a blood sample</li>
<li>Complete memory tests</li>
<li>Complete physical tests</li></ul>
*This study will last 5 years.
If you are interested, you have the choice of participating in either Durham, NC or Kannapolis, NC.
Locations
Pickett Road Research
Kannapolis
Other
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
Yes
Study Details
Full Title
PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults (All Site sIRB)
Study Website
Principal Investigator
Ranee
Chatterjee Montgomery
Protocol Number
PRO00103930
NCT ID
NCT04262206
Phase
IV
Enrollment Status
Open to Enrollment