If you choose to join this study, you will get a single dose of the study drug. The study drug is a type of intervention known as chimeric antigen receptor T cell (CAR-T) therapy. The study drug is made in a lab out of your own T cells that we will collect from your blood through a process called apheresis. This process involves passing your blood through a machine that removes T cells from the blood, and it then returns the rest of your blood products (e.g., red blood cells, white blood cells, plasma, and platelets) back to your body. Before you get the study drug, you will come to Duke Hospital for a "pre-conditioning" visit that will involve giving you two drugs called cyclophosphamide and fludarabine. These drugs are commonly used to pre-condition cancer patients who receive CAR-T therapy. There is evidence that these medications can help the CAR-T cells multiply more quickly in people's bodies and to remain longer. The study doctor may decide to have you stay in the hospital overnight after you get your pre-conditioning regimen. After pre-conditioning, we will schedule you to come in to get a dose of the study drug. The study drug is given as an infusion into a vein (IV). The study doctor might keep you in the hospital for up to 4 days after the infusion. This study is intensive and will require you and a caregiver of yours to stay within 1 hour of Duke Hospital for the first 14 days after the study drug infusion. We will schedule you to come in for follow-up visits after you get the study drug. Your participation might last for up to 15 years, but you will not need to make in-person visits after year 5.