Purpose of this Study
We are doing the Project HOPE study to better understand the health outcomes of moms and babies. We want to identify factors that contribute to poor birth outcomes, which might include premature both or low birthweight. We also want to learn more about what contributes to positive or negative maternal health outcomes, and longer-term child health and well-being outcomes, including academic achievement and physical development.
Who Can Participate?
Eligibility
Adults ages 18+ who:
- Are less than 23 weeks pregnant
- Expect to deliver only 1 baby
- Plan to use a Duke pediatrician after their child is born
Age Range
18-110
Sex/Genders
Female (cisgender)
Non-binary or gender fluid
Transgender male
Looking for Healthy Participants
No
What is Involved?
Description
If you choose to join this study, we will ask to collect several samples while you are pregnant and at the time you have your baby. These samples will be collected once per trimester and include:
- Blood
- Urine
- Microbiome samples
- Saliva
- Cord blood and placenta tissue (after you deliver your baby)
Locations
Other
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Project HOPE 1000: A Longitudinal Study of Mothers and Infants to Understand Health Outcomes Related to Pregnancy and Early-Life Exposures
Principal Investigator
Jennifer
Gilner
Protocol Number
PRO00100000
NCT ID
NCT04417283
Phase
N/A
Enrollment Status
Open to Enrollment