Purpose of this Study
After a one-time sample collection deidentified information about the study participants treatment and outcomes will be collected regularly from their medical records and entered into the Duke REDCap system for up to 8 years after enrolling in the study. Samples may be collected again if the study participant experiences a flare up of their disease.
Who Can Participate?
Eligibility
People can join this study if they are between 6 months and 21 years old and are being evaluated for a possible autoimmune brain disease, which is a condition where the immune system may mistakenly attack the brain. Participants must be willing to provide a blood sample or a cerebrospinal fluid sample if they are already having a spinal tap as part of their regular medical care. They must also be willing to complete questionnaires about their health and allow researchers to collect information from their past and future medical records.
Age Range
1-21
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No
What is Involved?
Description
The purpose of the study is to collect and store blood and cerebral spinal fluid from patients with suspected autoimmune brain diseases to look for biomarkers.
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
No
Spanish Materials Available
No
Study Details
Full Title
Pediatric Autoimmune Brain Disease: Prospective Study of Clinical Characteristics and Associated Biomarkers
Principal Investigator
Heather
Van Mater
Protocol Number
PRO00072941
Phase
Pilot
Enrollment Status
Open to Enrollment