If you join this study, you will receive shots after your surgery. The shots will contain either a medicine called inclisiran or a placebo, which has no medicine. You will get the first shot after surgery, then another shot at three months, and then every six months after that. You will come to the clinic for each shot. At these visits, the study team will ask about your health, side effects, and any medicines you are taking. You will also have blood tests at certain visits to check how your body is doing. You have an equal chance of receiving inclisiran or the placebo. The study is planned to last about three years.