Purpose of this Study
In this study, you will have three devices used on the outside of your body to measure how your heart is working, your blood pressure, and the pressure inside your heart. During your procedure, a thin tube will also be placed into a vein in your heart called the coronary sinus. It will be gently moved into the lower part of your heart to take measurements. Your heart will then be paced, and the measurements will be taken again. These extra steps will add about twenty minutes to your procedure.
Who Can Participate?
Eligibility
People can join this study if they are 18 years or older and are getting a left sided dual chamber or CRT heart device as part of their normal medical care.
Age Range
18-89
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No
What is Involved?
Description
This study wants to learn how a special kind of pacing, called transvenous diaphragmatic pacing, affects blood flow in the body. This pacing gently moves the left half of the diaphragm, which is the muscle that helps you breathe. Researchers want to see if this type of pacing can help the heart work as well as the regular kind of pacing that stimulates the left side of the heart.
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
TRANSvENous Diaphragmatic Pacing for Heart Failure:(TRANSCEND-HF)
Principal Investigator
Daniel
Friedman
Protocol Number
PRO00117436
Enrollment Status
Pending Open to Enrollment