Clinical Trials Directory

We are doing this study to find out if a drug called fluoxetine (the study drug) can cause changes to structures in your cells called lysosomes that then improve how well the chemotherapy drug temozolomide (TMZ) kills cancer cells in the brain. Lysosomes are organelles (structures in cells) that contain digestive enzymes (substances that break down chemicals) that help keep the cells free of extra or worn out cell parts. The study drug is approved by the FDA to treat problems like depression and anxiety, but we do not know if it also might be beneficial in treating cancer.

We are doing this study to learn more about the performance and safety of the Medtronic Hugo RAS (Robot Assisted Surgery) system when it is used to assist with urologic surgical procedures.

We are doing this study to examine genetic changes in your tumor that may contribute to resistance to immunotherapy. With this information, we hope to be able to identify new treatment methods as well as improve our ability to identify patients more likely to respond to immunotherapy.

We are doing this study is to find out if an investigational drug called imetelstat (the study drug) can lead to better outcomes in people who have myelofibrosis (MF) when it is compared to other available therapies.

We are doing this study to compare two different treatments to see which is better for treating children with this type of brain cancer. The drugs in this study have all be used to treat children with brain cancer, what is new is the way they are being given.

In addition to comparing how well these treatments work, we will evaluate their effects on each child's quality of life, brain function, and hearing.

We are doing this study to find out if giving the drugs floxuridine and oxaliplatin directly into the hepatic artery of the liver is a safe and effective option for patients with localized pancreatic ductal adenocarcinoma. This form of drug delivery will be combined with surgery and standard chemotherapy in this study. Chemotherapy can happen either before or after the delivery of drugs directly into the hepatic artery. We also want to see how this regimen works to improve the rate of liver metastasis (cancer that has spread to the liver) after surgery.

We are doing this study to learn more about the outcomes of people who get a transplant of cord blood stem cells versus people who get a transplant of adult donor stem cells. This study is important because we could learn more about different donor options for transplant patients.

We are doing this study to compare the outcomes of people who get their after-transplant care in the hospital versus in their home. This study is important to learn if getting after-transplant care in a patient's home can lead to better outcomes.