IIT: Cord Blood Attenuates Accelerated Aging after Hematopoietic Stem Cell Transplantation

Purpose of this Study

We are doing this study to learn more about the outcomes of people who get a transplant of cord blood stem cells versus people who get a transplant of adult donor stem cells. This study is important because we could learn more about different donor options for transplant patients.

Who Can Participate?

Eligibility

Adults ages 19-80 who had an allogeneic (donor cells) stem cell transplant at least 1 year ago.

For more information about who can join this study, please contact the study team at lauren.bohannon@duke.edu or 919-668-2369.

Age Range

19-90

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No

What is Involved?

If you choose to join the study, you will:
- Visit our clinic 2 times
- Fill out questionnaires
- Complete physical function assessments
- Have Cardiopulmonary Exercise Testing (CPET) done
- Have your muscles scanned with a handheld ultrasound device
- Give stool samples
- Have your skin swabbed
- Have blood draws
- Have a biopsy of your muscle taken (optional)
- Have a biopsy of your skin taken (optional)

Locations

Duke University Hospital

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

IIT: Cord Blood Attenuates Accelerated Aging after Hematopoietic Stem Cell Transplantation

Principal Investigator

Anthony
Sung

Protocol Number

PRO00104210

Phase

N/A

Enrollment Status

OPEN TO ACCRUAL