Clinical Trials Directory

222 clinical trials found.
Brain and Spine Metastasis

We are doing this study to find out if an experimental drug called APL-5125 (the study drug) is a safe and effective for people with select types of gastrointestinal cancer. We are also trying to find the best dose of APL-5125 to use.

Compensation: No
Oncology
Gastrointestinal Cancer

We are doing this study to see if the study drugs, domvanalimab and zimberelimab, are safe and effective for treating advanced or metastatic gastroesophageal adenocarcinoma.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Breast Cancer

We are doing this study to find out if a study drug called sacituzumab govitecan can improve outcomes for patients with high risk, early triple negative breast cancer (TNBC). We want to know if giving this drug in combination with pembrolizumab will work better than pembrolizumab on its own or better than pembrolizumab + capecitabine.

Compensation: No
Oncology
Gastrointestinal Cancer

We are doing this study to find out if an experimental drug called ASP2138 (the study drug) is a safe and effective option for people with gastroesophageal junction (GEJ) cancer or metastatic pancreatic cancer.

Compensation: No
Oncology
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an experimental drug called tabelecleucel is effective for the treatment of EBV-associated post-transplant lymphoproliferative disease (EBV+ PTLD). We want to know if it is beneficial for people with EBV+PTLD who have received either a solid organ transplant or an allogeneic hematopoietic cell transplant.

Compensation: No
Oncology
Skin Cancer - Melanoma

We are doing this study to find out if a study drug called belzupacap sarotalocan (bel-sar) is a safe and effective option when it is combined with laser light therapy for people who have a type of eye cancer called an indeterminate lesion (a growth in your eye that is suspected to be melanoma) or choroidal melanoma, which is also known as eye melanoma.

Compensation: Yes
Ages: 18-110
Oncology
Duke University Hospital
Skin Cancer - Melanoma

We are doing this study to find out if an experimental drug called MK-4280A (the study drug) is a safe and effective option for people who are diagnosed with different types of solid tumors. We are enrolling Arm A of this study, which is open to people diagnosed with cutaneous squamous cell carcinoma (cSCC).

Compensation: No
Ages: 18-110
Oncology
Duke University Hospital, Duke Raleigh Hospital
Hematologic Malignancies and Cellular Therapy

We are doing this study to find out if an investigational drug called TP-3654 (the study drug) is a safe and effective treatment for myelofibrosis. The study drug will be tested at different doses to find out what effects, if any, it has on myelofibrosis.

Compensation: No
Oncology