DMID 24-0024 (Avian (H5) Influenza Vaccination)

Purpose of this Study

We are doing this study to find out if an experimental vaccine is a safe and effective option to protect against H5 avian influenza (bird flu).

Who Can Participate?

Eligibility

Adults ages 18-49 who:
  • Are in good general health
  • Do not have any form of autoimmune disease
  • Do not have regular contact with chickens or cattle
For more information about this study, contact the study team at stephanie.smith@duke.edu.

Age Range

18-49

Sex/Genders

Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
Yes

What is Involved?

Description

If you choose to join this study, you will:
  • Have a screening visit to confirm your eligibility
  • Get 2 doses of the study vaccine about a month apart from each other
  • Fill out surveys once a day for 7 days after each vaccination visit
  • Visit our clinic up to 5 times for follow-up visits after getting the study vaccine

Locations

Other

Visit Timing

Weekdays

Compensation

Yes

Spanish Materials Available

No

Study Details

Full Title

A Phase 1 Study to Evaluate the Safety and Immunogenicity of Two Doses of a Novel H5 Antigenically Central (AC)-Anhui mRNA-LNP Vaccine in Healthy Adults

Principal Investigator

Emmanuel
Walter

Protocol Number

PRO00117755

Phase

I

Enrollment Status

Open to Enrollment