Purpose of this Study
We are doing this study to find out how see how easy or difficult it is to complete a hybrid (virtual and in-person) personalized exercise training program for older adults with sickle cell disease. The virtual training sessions will be done primarily on Zoom. This research is important to determine ways to improve movement capacity, heart health, strength, and quality of life in older adults living with sickle cell disease.
Who Can Participate?
Eligibility
Adults ages 40+ who:
- Are diagnosed with sickle cell disease
- Do not need supplemental oxygen
- Do not use a wheelchair
- Do not have any type of unstable heart condition
For more information about this study, please contact the study team at SICKLEFIT@duke.edu.
- Are diagnosed with sickle cell disease
- Do not need supplemental oxygen
- Do not use a wheelchair
- Do not have any type of unstable heart condition
For more information about this study, please contact the study team at SICKLEFIT@duke.edu.
Age Range
40-110
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No
What is Involved?
If you choose to join this study, participation will involve 4 in-person visits to our clinic. The virtual exercise program lasts for 12 weeks.
In-person visits (completed every three months) include:
- Surveys about living with sickle cell disease and motivation for exercise
- A functional assessment of walking speed, a six-minute walk test, core strength, grip strength, and chair stands
- Blood draws and urine collection
The virtual exercise sessions will:
- Happen 3 days a week
- Include a warmup, mobility/stretching, cardio, strength training, and mindfulness/yoga
- Be scaled and personalized by a dedicated fitness instructor, which means we will provide modifications for your personal level of fitness
In-person visits (completed every three months) include:
- Surveys about living with sickle cell disease and motivation for exercise
- A functional assessment of walking speed, a six-minute walk test, core strength, grip strength, and chair stands
- Blood draws and urine collection
The virtual exercise sessions will:
- Happen 3 days a week
- Include a warmup, mobility/stretching, cardio, strength training, and mindfulness/yoga
- Be scaled and personalized by a dedicated fitness instructor, which means we will provide modifications for your personal level of fitness
Locations
Duke University Hospital
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Gerofit Exercise Intervention for Older Adults with Sickle Cell Disease
Principal Investigator
Charity
Oyedeji
Protocol Number
PRO00111833
NCT ID
NCT05714098
Phase
Pilot
Enrollment Status
OPEN TO ACCRUAL