Purpose of this Study
We are doing this study to get a better understanding of why people are at higher risk of developing arthritis after ACL reconstruction surgery. We hope the information from this study can help improve recovery techniques and lower the risk of developing knee arthritis for people who have ACL surgery. We are partnering with UNC-Chapel Hill to do this study.
Who Can Participate?
Eligibility
Adults and children ages 16-35 who:
- Have an ACL tear and are planning to have ACL reconstruction surgery at Duke; OR
- Had a previous ACL tear and reconstruction surgery and are planning to have a revision surgery at Duke
For more information about who can join this study, please contact the study team at cassandra.rhodes@duke.edu.
- Have an ACL tear and are planning to have ACL reconstruction surgery at Duke; OR
- Had a previous ACL tear and reconstruction surgery and are planning to have a revision surgery at Duke
For more information about who can join this study, please contact the study team at cassandra.rhodes@duke.edu.
Age Range
18-50
Sex/Genders
Male (cisgender)
Female (cisgender)
Non-binary or gender fluid
Transgender male
Transgender female
Looking for Healthy Participants
No
What is Involved?
If you choose to join this study, you will visit a study clinic at UNC one time before your surgery to have some physical assessments done for your injured leg. You will return to the UNC clinic for 4 follow-up visits at the following times: 2, 4, 6, and 12 months after your surgery. During these follow-up visits, you will:
- Have blood draws
- Give urine samples
- Answer questionnaires
- Have images (MRI and X-ray) taken of your injured knee and leg
- Do a variety of physical movement and strength tests
We will pay you for your time on the study.
- Have blood draws
- Give urine samples
- Answer questionnaires
- Have images (MRI and X-ray) taken of your injured knee and leg
- Do a variety of physical movement and strength tests
We will pay you for your time on the study.
Locations
Duke University Hospital
Other
Visit Timing
Weekdays
Compensation
Yes
Spanish Materials Available
No
Study Details
Full Title
Biomechanical Changes Following ACL Injury that Influence PTOA
Principal Investigator
Brian
Lau
Protocol Number
PRO00111706
Phase
N/A
Enrollment Status
OPEN TO ACCRUAL