Purpose of this Study
We are doing this study to find out if an experimental product called cryopreserved platelets (CPP) can help control the bleeding that happens during and after cardiopulmonary bypass surgery. We want to see how well this product works in comparison to the standard therapy that is used to control bleeding during surgery, which is liquid stored platelets (LSP).
Who Can Participate?
Eligibility
Adults who are scheduled or referred to have cardiopulmonary bypass surgery at Duke.
For more information about who can join this study, please contact the study team at dana.giangiacomo@duke.edu.
For more information about who can join this study, please contact the study team at dana.giangiacomo@duke.edu.
What is Involved?
If you choose to join this study you will:
- Get a random assignment (like a coin flip) to either receive CPP or LSP during your surgery
- Have blood draws
- Have a follow-up phone call with the study team 30 days after your surgery
- Get a random assignment (like a coin flip) to either receive CPP or LSP during your surgery
- Have blood draws
- Have a follow-up phone call with the study team 30 days after your surgery
Study Details
Full Title
Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery (CRYPTICS)
Principal Investigator
Jeffrey
Keenan
Protocol Number
PRO00109067
NCT ID
NCT04709705
Phase
II/III
Enrollment Status
OPEN TO ACCRUAL