CRYPTICS (Cardiopulmonary Bypass Surgery)

Purpose of this Study

We are doing this study to find out if an experimental product called cryopreserved platelets (CPP) can help control the bleeding that happens during and after cardiopulmonary bypass surgery. We want to see how well this product works in comparison to the standard therapy that is used to control bleeding during surgery, which is liquid stored platelets (LSP).

Who Can Participate?

Eligibility

Adults who are scheduled or referred to have cardiopulmonary bypass surgery at Duke.

For more information about who can join this study, please contact the study team at dana.giangiacomo@duke.edu.

What is Involved?

If you choose to join this study you will:
- Get a random assignment (like a coin flip) to either receive CPP or LSP during your surgery
- Have blood draws
- Have a follow-up phone call with the study team 30 days after your surgery

Study Details

Full Title

Randomized Controlled Trial Comparing Dimethyl Sulfoxide Cryopreserved Platelets to Liquid Stored Platelets in Patients Undergoing Cardiopulmonary Bypass Surgery (CRYPTICS)

Principal Investigator

Jeffrey
Keenan

Protocol Number

PRO00109067

NCT ID

NCT04709705

Phase

II/III

Enrollment Status

OPEN TO ACCRUAL